December 2024
To understand potential disparities in the use of glucagon-like peptide-1 receptor agonists (GLP–1 RAs) across social determinants of health (SDoH) domains among pediatric patients.
December 2024
To investigate reasons behind discontinuation and switching of biologic treatments for inflammatory bowel disease (IBD) leveraging large language models (LLMs) applied to unstructured clinical notes from electronic health records (EHRs).
December 2024
To understand reasons for discontinuation (r/dc) of Ozempic (semaglutide) through natural language processing (NLP) of clinical notes from electronic health records..
December 2024
To characterize the clinical management of actinic keratosis (AK) in the real-world setting by disease severity as measured by the 0 to 10-point pain visual analogue scale (VAS) and the lesion count.
June 2024
The objective of this research was to characterize type 2 diabetes (T2D) patients initiating semaglutide and tirzepatide and to describe subsequent weight loss and change in body mass index (BMI) in the real-world setting.
June 2024
As structured social determinant of health (SDoH) measures are often unavailable in real–world health data, one potential solution is to use n-gram models run on unstructured clinical notes to predict the existence of SDoH risk factors. Our objective was to investigate the credibility of an n-gram model in predicting economic instability.
June 2024
Social determinants of health (SDoH) are increasingly leveraged in health research. However, availability of structured SDoH data is limited in electronic health records. Our objective was to implement and validate the use of n-gram models using unstructured clinical notes to classify patient risk status across five key SDoH domains.
June 2024
The objective of this research was to utilize only prescription and procedure data from electronic health records (EHRs) to distinguish moderate and severe plaque psoriasis (PsO) from mild PsO in patients from specialty dermatology networks in the United States.
June 2024
First line treatment for diabetic macular edema (DME) patients tends to be intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy. However, many patients do not adequately respond to anti-VEGF therapy. Corticosteroid implants may be considered a second line therapy for these patients. No clear guidelines for switching a patient from anti-VEGF to corticosteroid implant therapy have been established.
June 2024
Social determinants of health (SDoH) burden has been correlated with disparities in care access and risk of health issues. Using self-reported information about economic security captured in the electronic health record (EHR), we investigated the hypothesis that insecurity would be associated with higher utilization and chronic disease prevalence.
June 2024
The objective of this research was to predict the Psoriasis Area and Severity Index (PASI) for patients in the real-world dermatology setting using only physician global assessment (PGA) and body surface area (BSA).
December 2023
Ankylosing spondylitis (AS) is an inflammatory disease affecting the spine with multisystemic implications. The objective of this research was to characterize treatment patterns of AS patients in the real-world setting.
December 2023
The objectives of this research were to describe underlying demographic, clinical, and disease activity characteristics of generalized pustular psoriasis (GPP) patients by flare status and to characterize the timing and frequency of GPP flares.
December 2023
To train and apply a natural language processing (NLP) model on clinical notes to identify economic insecurity among psoriasis patients and to compare findings to those of using structured clinical codes.
December 2023
The objective of this research was to characterize real-world treatment patterns among bullous pemphigoid patients in diverse healthcare delivery settings in the United States (US).
December 2023
Pruritus is a cutaneous symptom but could be a manifestation of a wide range of systemic conditions making it difficult to manage. Itch intensity is a measure of symptom severity and can influence management. The objective of this research was to understand the influence of itch intensity on therapeutic management of pruritus in the real-world setting.
December 2023
Long-term health effects of chronic SARS-CoV-2 infection (long COVID) are receiving increasing recognition, but clinical understanding and management remain in flux. An ICD-10-CM code for long COVID was deployed in October 2021. The objective of this research was to characterize demographics, concurrent diagnoses, and treatment patterns among patients with a long COVID diagnosis code in the United States.
June 2023
Therapeutic management of localized scleroderma (LSc) is not standardized and generally unsatisfactory. The objective of this research was to characterize real-world treatment patterns among LSc patients in diverse healthcare delivery settings in the United States.
June 2023
Diabetic retinopathy (DR) is a leading cause of blindness. Anti-vascular endothelial growth factor (anti-VEGF) therapy has become a primary line of treatment for patients with diabetic retinopathy. The objective of this research was to characterize patients at the initiation of anti-VEGF therapy in diverse healthcare settings in the United States.
June 2023
To compare healthcare resource utilization (HCRU) between natural language processing (NLP)-identified hormone receptor (HR)–positive and negative breast cancer patients in the real-world setting.
June 2023
Severity of psoriasis is a major factor in a physician’s treatment decision. The objective of this research was to evaluate the relationship between the Physician Global Assessment and Body Surface Area product (PGA x BSA) and the Psoriasis Area and Severity Index (PASI) for assessing disease activity in psoriasis patients in specialty dermatology networks in the United States (US).
June 2023
The objective of this research was to characterize ocular curvature (OC), intraocular pressure (IOP), and best-corrected visual acuity (BCVA) at the onset of wet age-related macular degeneration (AMD), dry AMD, dry eye syndrome (DES), and glaucoma in the real-world setting.
December 2022
Our objective was to evaluate the relationship between bullous pemphigoid (BP) disease activity (DA), as measured by body surface area (BSA) and physician global assessment (PGA), and systemic therapy initiation (STI).
December 2022
Our objective was to describe patient characteristics and real-world treatment patterns among age-related cataract patients in diverse healthcare delivery settings in the United States.
December 2022
The objective of this research was to characterize real-world treatment patterns among wet age-related macular degeneration (wet AMD) patients in diverse healthcare delivery settings in the United States (US).
December 2022
Our goal was to determine the accuracy of a pretrained Albert-for-Question-Answering model for extraction of ejection fraction (EF) values from relevant sentences for patients having congestive heart failure.
December 2022
The objective of this study was to identify and quantify the occurrences of concepts related to social determinants of health (SDoH) at the patient level captured in unstructured clinical notes from electronic health records (EHRs).
June 2022
Our objective was to evaluate the relationship between atopic dermatitis (AD) disease activity (DA), as measured by body surface area (BSA) and physician global assessment (PGA), and systemic therapy initiation (STI).
June 2022
The objective of this research was to characterize real-world treatment patterns among alopecia areata (AA) patients in diverse healthcare delivery settings in the United States
June 2022
The objective of this research was to characterize demographics, disease severity, treatment, and associated comorbidities among pediatric hidradenitis suppurativa (HS) patients in diverse healthcare delivery settings in the United States (US).
June 2022
The objective of this research was to describe secular trends in the use of biologics for the treatment of psoriatic arthritis (PsA) using real-world data.
June 2022
The objective of this research was to characterize real-world treatment patterns among vitiligo patients in diverse healthcare delivery settings in the United States (US) given the lack of Food and Drug Administration-approved treatments.
June 2022
The objective of this research was to characterize real-world treatment patterns among hidradenitis suppurativa (HS) patients in diverse healthcare delivery settings in the United States (US).
June 2022
The objective of this research was to characterize the use of cosmetic dermatology products in patients seen at specialty dermatology networks in the United States (US).
December 2021
The objective of this research was to characterize real-world treatment patterns of traditional and advanced therapies among atopic dermatitis (AD) patients in large dermatology specialty networks in the United States (US).
May 2021
The effectiveness of commercial clinical named entity recognition (NER) systems in recognizing COVID-19-related concepts is not well understood. The objective of this study was to measure the performance of the Amazon Comprehend Medical ICD-10-CM Ontology Linking API (ACM-ICD10) for detecting the presence of COVID-19-related concepts in a clinical document sample obtained from COVID-19 positive patients.
May 2021
The objective of this research is to characterize the hospital experience of patients diagnosed with COVID-19 in the real-world setting.
May 2021
Clinical trials evaluating negative pressure wound therapy (NPWT) as a treatment for pressure ulcer (PU) have been inconclusive. The objective of this research was to evaluate the effect of NPWT on length of stay (LOS), charges, and mortality for PU patients.
May 2021
The objective of this study is to evaluate the relationship between psoriasis severity, as measured by the affected body surface area (BSA), and the initiation of systemic therapy.
